Does combining Bio-HRT with Semaglutide help with post-menopausal weight loss?

A new study published in Menopause in April 2024¹ compared the weight loss response and cardio-metabolic risk markers in post-menopausal women using Semaglutide, with and without menopause hormone therapy (or Bio-HRT). This retrospective cohort study followed 106 postmenopausal women for 12 months. The conclusion was that Semaglutide with Bio-HRT was associated with an improved weight loss response in overweight or obese post-menopausal women compared to Semaglutide alone.²

Dr. Rao’s Insights on Post-Menopausal Weight Loss:

This study highlights the synergistic approach we have promoted since 2000 for women’s health. Our personalized recommendations have consistently yielded the best results. It’s when 1 plus 1 equals 3! It’s always encouraging to see research supporting our approach.

Two Crucial Points to Consider:

1. Ozempic Face: Many women using Semaglutide alone may experience the so-called “Ozempic Face.” This occurs because, while peripheral and visceral fat may be lost, muscle mass and bone mass loss still occur.
2. Post-Menopausal Obesity: Most women will spend a significant portion of their lives post-menopausal, a time when many become obese or morbidly obese.

Our Comprehensive Approach to Post-Menopausal Weight Loss

From the start, we have never promoted a single magic pill, cream, or shot. It takes a comprehensive, personalized approach that includes lifestyle intervention—proper exercise and diet, hormonal optimization starting in midlife, and, if needed, anti-obesity medications (AOMs). But not just AOMs alone. This way, we not only achieve weight loss but also improve body composition, which includes muscle and bone mass.

If you don’t address muscle and bone mass, you’re missing two-thirds of the battle. Our approach combines lifestyle changes, proper exercise and diet, hormonal optimization, and, if necessary, weight loss medications customized to your needs. This leads to optimized health in the safest way, for both men and women.

Benefits of Our Program

With our programs, weight control becomes easier, as you’re no longer fighting an uphill battle. The earlier you start, the better! Don’t wait until after menopause. With our personalized, comprehensive programs, you’ll see improvements not only in weight loss and control but also in sexual health, mood, energy, sense of well-being, and more. It’s all detailed in my books. No matter what stage of life you’re in—pre-, peri-, or post-menopausal—we can help you as we have helped many others. Our experience and track record speak for themselves.

Take Action Now:

Call or email us NOW to start your transformative journey toward optimal health in the safest, most effective way! Why wait?

1. Hurtado M, MD PhD, et al. Weight loss in response to semaglutide and postmenopausal women with and without hormone therapy use. Menopause 30(4); p 266–274, April 2024. ↩︎
2. This association was maintained when adjusted for confounders. They suggested larger studies should be conducted to confirm these results.  ↩︎